Normalized Diastolic Properties After Left Ventricular Assist Result From Reverse Remodeling of Chamber Geometry
نویسندگان
چکیده
منابع مشابه
Normalized diastolic properties after left ventricular assist result from reverse remodeling of chamber geometry.
BACKGROUND Normalization of diastolic properties after left ventricular (LV) assist may result from a change in myocardial material properties, chamber size, or both. This study tested the hypothesis that reported normalization of LV diastolic properties is primarily due to remodeling of chamber geometry. METHODS AND RESULTS Hearts were obtained at transplantation from 8 patients with dilated...
متن کاملLeft ventricular assist device-induced reverse ventricular remodeling.
Left ventricular assist devices provide chronic pressure and volume unloading of the dilated left ventricle in patients with end-stage heart failure. This is associated with reverse structural remodeling (normalization of the passive pressure-volume relationship), reverse molecular remodeling (increased expression of several genes involved in calcium metabolism that are down-regulated in heart ...
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1. Stoica SC, Cafferty F, Pauriah M, et al. The cumulative effect of acute rejection on development of cardiac allograft vasculopathy. J Heart Lung Transplant 2006;25:420-5. 2. Gilad S, Meiri E, Yogev Y, et al. Serum microRNAs are promising novel biomarkers. PLoS One 2008;3:e3148. 3. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004;116:281-97. 4. Shan J, Feng L, Lu...
متن کاملComparison of left ventricular geometry after HeartMate II and HeartWare left ventricular assist device implantation
BACKGROUND HeartMate II (HM II) and HeartWare (HW) Left Ventricular Assist Devices have been successfully used in end-stage heart failure patients as a bridge to transplantation, recovery, or decision. We set out to compare their effect in off-loading the left ventricle and its geometry. METHODS The left ventricular end diastolic (LVEDD) and end systolic (LVESD) diameters were compared betwee...
متن کاملChamber properties from transmitral flow: prediction of average and passive left ventricular diastolic stiffness.
A chamber stiffness (K(LV))-transmitral flow (E-wave) deceleration time relation has been invasively validated in dogs with the use of average stiffness [(DeltaP/DeltaV)(avg)]. K(LV) is equivalent to k(E), the (E-wave) stiffness of the parameterized diastolic filling model. Prediction and validation of 1) (DeltaP/DeltaV)(avg) in terms of k(E), 2) early rapid-filling stiffness [(DeltaP/DeltaV)(E...
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ژورنال
عنوان ژورنال: Circulation
سال: 2001
ISSN: 0009-7322,1524-4539
DOI: 10.1161/hc37t1.094914